All explainers
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Learning to Live With IBD: What a Cochrane Review Found About Patient Education Programs
A 2023 Cochrane systematic review examined the trial evidence for structured patient education interventions in inflammatory bowel disease, assessing whether programmes delivered by nurses, clinicians, or digital tools affect disease activity, quality of life, and patients' ability to manage their own condition.

Telehealth for IBD: What a Cochrane Review Found About Remote Care
A Cochrane systematic review evaluated whether digital and remote care tools, including apps, telephone follow-up, and web-based monitoring platforms, change outcomes for people living with inflammatory bowel disease. Here is what the evidence found, and why certainty still matters.

After Crohn's Surgery: The Growing Case for Intestinal Ultrasound as a Monitoring Tool
A 2026 international consensus study published in The Lancet Gastroenterology & Hepatology used the RAND/UCLA appropriateness method to evaluate exactly when intestinal ultrasound is appropriate for detecting postoperative Crohn's disease recurrence, drawing on 21 international experts to produce the first structured guidance on this non-invasive monitoring approach.

Azathioprine and 6-MP for Ulcerative Colitis: A 2025 Cochrane Review on Long-Term Remission
A 2025 Cochrane systematic review synthesises randomised trial evidence on azathioprine and 6-mercaptopurine for maintaining remission in ulcerative colitis. These widely used medications have decades of clinical history, but patients often have questions about what the evidence actually shows and what routine monitoring involves.

When One IBD Treatment Is Not Enough: A 2026 Review on Combining Biologics
A systematic review and meta-analysis pooling 52 studies and 2,022 participants found early safety signals for combining two advanced IBD drugs, but the certainty of evidence is rated very low across all analyses.

Vitamin D and IBD: What a Cochrane Review of 22 Trials Found — and What Remains Uncertain
A 2023 Cochrane systematic review examined 22 randomised controlled trials with 1,874 participants living with IBD. The review found a possible reduction in clinical relapse with vitamin D supplementation — but rates certainty of evidence as low, and cannot yet draw conclusions on quality of life or disease response.

Psychological Support for IBD: What a Cochrane Review of 68 Studies Shows About Therapy, Education, and Relaxation
A 2025 Cochrane systematic review and meta-analysis of 68 randomised trials found that psychotherapy, patient education, and relaxation techniques each produce small but meaningful improvements in quality of life, depression, and anxiety for adults living with inflammatory bowel disease.

Does cannabis help inflammatory bowel disease? What a June 2026 systematic review of THC actually found
Cannabis is one of the most widely used self-treatments among people with IBD, but a new systematic review built to Cochrane standards found that THC-containing cannabis showed no effect on remission or endoscopic healing — only low-certainty signals for bloating and appetite — and concluded that the overall evidence remains inconclusive.

Life after pelvic exenteration: what a 2026 systematic review of 23 studies says about quality of life, body image, and living with a stoma
Pelvic exenteration is one of the most radical operations in gynaecological cancer care, and it usually leaves a person with one or two stomas. A 2026 systematic review brought together 23 studies (1,655 patients) on quality of life afterward. The honest picture: overall quality of life often stabilised or recovered beyond six months, but sexual function, body image — frequently tied to stoma formation — and psychological distress commonly stayed worse. No randomized trials existed and most studies carried a serious risk of bias, so this is a careful synthesis of observational evidence, not proof of cause.

When the tumour sits very low: what a 2026 review says about sphincter-preserving surgery for rectal cancer
For rectal cancers very close to the anus, the hardest surgical question is whether the muscle that gives you control — the sphincter — can be kept, or whether removing it (and living with a permanent colostomy) is the safer way to clear the cancer. A 2026 narrative review surveys six sphincter-preserving techniques: most reach acceptable cancer-control outcomes, but bowel function afterwards stays the main concern, and the newest method rests on small studies. This is a survey of options, not a ranking — and the right answer is individual.

Does filling the colon with water make colonoscopy easier? What a 2026 systematic review and meta-analysis of 30 trials actually found
Water infusion — filling the colon with warm water instead of air or CO2 — has been studied as a gentler way to do a colonoscopy. A 2026 systematic review and meta-analysis pooled 30 randomized trials: it found no difference in adenoma detection, reaching the cecum, or procedure time, but fewer people needed on-demand sedation (risk ratio 0.61) or abdominal pressing (risk ratio 0.65). A comfort finding, not a detection upgrade — and whether it's offered depends on your endoscopy unit.

Ear, nose and throat signs in IBD: what a 2026 systematic review actually documents
Joints, eyes and skin are the extraintestinal manifestations of inflammatory bowel disease that most people have heard of. A 2026 systematic review pulls together the ear, nose and throat side of the picture — uncommon, mostly documented in small case series, but consistent enough that the authors think clinicians should be looking.